01 - Preheat oven to 425°F. Line a large baking sheet with parchment paper or lightly grease with cooking spray.
02 - In a large bowl, whisk together the flour, water, garlic powder, onion powder, smoked paprika, salt, and black pepper until smooth and well combined.
03 - Add cauliflower florets to the batter. Toss gently until each piece is evenly coated with the batter mixture.
04 - Place panko breadcrumbs in a shallow bowl. Dip each battered floret into breadcrumbs, pressing gently to ensure the coating adheres thoroughly.
05 - Arrange coated cauliflower in a single layer on the prepared baking sheet. Bake for 20 minutes, turning once halfway through cooking time, until golden and crispy.
06 - While cauliflower bakes, whisk together hot sauce, melted butter, and honey or maple syrup (if using) in a small bowl until fully incorporated.
07 - Remove baked cauliflower from oven. Transfer to a clean bowl and toss gently with buffalo sauce until evenly coated.
08 - Return sauce-coated cauliflower to the baking sheet. Bake for an additional 5 to 8 minutes until edges are crispy and sauce is set.
09 - Serve immediately while hot and crispy. Accompany with ranch or blue cheese dressing, celery sticks, and carrot sticks if desired.